A prefix is a group of letters that is added to the beginning of a word (known as the base word or stem word) to create another word.

Most prefixes are set solid with the base word:

aero- (aeroplane)electro- (electromagnet)meta- (metadata)pre- (preoperative)    
after- (afterthought)en- (encode) micro- (microorganism)    pro- (pronoun)
ante- (antenatal)exo- (exoskeleton)mid- (midterm)    pseudo- (pseudofluid)
anti- (antibody)extra- (extramarital)milli- (millimetre)re- (readmit)    
astro- (astronaut)geo- (geographic)mini- (miniskirt)     semi- (semidetached)     
auto- (autosuggestion)hemi- (hemisphere)multi- (multitalented)stereo- (stereophonic)
bi- (bipolar)hyper- (hyperactive)     nano- (nanoparticle)   sub- (subsystem)    
bio- (biodata)hypo- (hypoglycaemic)non- (nongovernment)    super- (supermarket)    
centi- (centipede)in- (inflexible)para- (paramilitary)    supra- (supraorbital)
chemo- (chemotherapy)infra- (infrared)photo- (photograph)trans- (transgender)    
co- (cochair)inter- (interdisciplinary)physio- (physiotherapy)tri- (trilateral)    
counter- (counterterrorism)intra- (intravenous)phyto- (phytoactive)ultra- (ultrasound)   
di- (diode)iso- (isotope)poly- (polyunsaturated)    un- (unflagging)    
dis- (disinherit)macro- (macroeconomics)post- (postnatal)under- (underestimate)

When the base term consists of more than 1 word, use an en dash after the prefix instead of a hyphen (see En dash):

the post–French Revolution period     pro–women’s rights

However, if the base term itself has a hyphen, use a hyphen after the prefix:

non-English-speaking people   not   non–English speaking people

Exceptions for hyphens with prefixes

Use a hyphen after the prefix when:

  • the word formed would otherwise be confused with another word
pre-fix/prefix     re-cover/recover     re-mark/remark     un-ionised/unionised
  • the combination of the prefix and the base word would create an unacceptable double or triple vowel in the middle of the word

ultra-aerated   not   ultraaerated

anti-aircraft   not   antiaircraft

  • the boundary between 2 parts of the word would otherwise be obscured

sea-legs   not   sealegs

non-event   not   nonevent

  • the base word begins with a capital letter or is a number
mid-1990s     non-Indigenous     post-2010     trans-Atlantic     un-Australian   
  • the prefix is e- (short for electronic), except for more established forms
e-book     e-health     e-learning   but   email
  • the prefix is ex- (meaning former)
ex-boyfriend     ex-student     ex-wife    
  • the prefix or first part of the word is cross, except for more established forms
cross-reference     cross-section     cross-country   but   crossover     crossbreed
  • the prefix or first part of the word is self-
self-conscious     self-awareness     self-destructive   but   selfless     unselfconscious

Did you know? Cooperate and coordinate started out with hyphens (co-operate, co-ordinate), to indicate that the 2 o’s did not form a double o.

These are now so familiar that confusion is unlikely, so they are set solid.